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A Complete Payment
Operating System
for Clinical Trials

Six integrated modules that transform raw trial execution data into verified, compliant, auditable payments — without manual intervention at any stage of the process.

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01

Budget Intelligence Engine

The authoritative source of truth for trial payment authorization. Ingests and structures all budget instruments — from protocol schedules to site-level negotiated rates — into a dynamic, queryable authorization baseline.

  • Structured ingestion of protocol budget schedules and amendments
  • Site-specific negotiated rate management and version control
  • Per-procedure, per-visit, per-patient payment authorization tables
  • Amendment tracking with effective-date intelligence
  • Multi-currency budget normalization across study portfolios
  • Budget Versioning Amendment Management Rate Tables Multi-Currency
    Budget Intelligence — Study Overview Live
    SiteProtocolBudget Auth.Rate VersionStatus
    SGH SingaporeCTR-2401$284,500v2.1 Active
    NUH SingaporeCTR-2401$312,200v2.1 Active
    RNSH SydneyCTR-2401$198,000v2.0 Review
    AIIMS DelhiCTR-2401$145,600v2.1 Active
    Seoul NUHCTR-2401$267,800v1.9 Amend. Pending
    📊
    EDC Systems
    Electronic Data Capture
    Connected
    🏥
    Site Portal
    ClinTrust Site Dashboard
    Native
    02

    Multi-Source Execution Capture

    A unified data ingestion layer that aggregates visit completions, protocol milestones, patient enrollments, and adverse events from all clinical trial data sources into a single, structured execution ledger.

  • Native connectors for major EDC platforms
  • Real-time event streaming with webhook support
  • Data normalization across heterogeneous source schemas
  • Immutable execution event log with full data lineage
  • EDC Connectors Site Portal API Execution Ledger
    03

    AI-Assisted Reconciliation

    Our AI engine matches execution events to budget line items with explainable confidence scoring. Every reconciliation decision includes a full audit trail — no black-box processing, no unattributed matches.

    🔍
    Explainable Decisions
    Every match includes the data sources, rules applied, and confidence basis — reviewable by compliance teams.
    📈
    Confidence Scoring
    Matches are scored 0–100% with automatic routing — high-confidence to auto-approve, low-confidence to human review.
    🛡️
    Regulatory Grade Lineage
    Full audit chain from source data event to payment authorization — meets 21 CFR Part 11 and ICH E6(R3) requirements.
    AI Reconciliation Engine — Live Queue Running
    Visit V8 — Patient #0042 — SGH
    Matched → CTR-2401 V8 Completion Fee
    97%
    $1,840
    Auto-approved
    Lab Panel LP-09 — Patient #0038 — NUH
    Matched → CTR-2401 Central Lab Processing
    94%
    $320
    Auto-approved
    AE Management — Patient #0051 — RNSH
    Possible match → Unscheduled Visit Fee
    71%
    $690
    Pending review
    Visit V4 — Patient #0063 — AIIMS
    Matched → CTR-2401 V4 Assessment Bundle
    99%
    $2,105
    Auto-approved
    Execution Event Verified
    AI reconciliation confirms visit completion and budget match at 95%+ confidence
    T+0
    📋
    Payable Formed
    Structured payable record created with full data lineage, authorization reference, and compliance metadata
    T+minutes
    Sponsor Authorized
    Pre-configured authorization rules route for approval — or auto-authorize within agreed thresholds
    T+hours
    💸
    Payment Queued
    Payable enters funding orchestration for disbursement via local payment rail
    Same-day
    04

    Continuous Payable Formation

    Payables are formed in real-time as execution events are verified — replacing end-of-month batch invoicing with a continuous, event-driven payment formation engine that eliminates queuing delays.

  • Real-time payable formation on execution event confirmation
  • Eliminates invoice generation and submission cycles
  • Configurable authorization thresholds for auto-approval
  • Payable batching for operational efficiency at sponsor discretion
  • Immutable payable register with full compliance metadata
  • 05

    Dynamic Funding Model

    Replaces fixed, oversized escrow accounts with execution-calibrated funding buffers. The funding engine monitors payable velocity and dynamically adjusts capital requirements — reducing idle capital by 70–80% while maintaining continuous payment availability.

    Traditional
    $20M Fixed Escrow ~$12M unused
    Fixed advance regardless of execution rate
    ClinTrust.ai
    $5M Active Buffer
    Replenished as payments clear
    Adaptive buffer calibrated to execution velocity
    70–80% Escrow Reduction Velocity-Based Calibration Continuous Availability
    Funding Dashboard — CTR-2401 Portfolio Real-Time
    $5M
    Active Buffer
    $2.1M
    Queued Payables
    $15M
    Freed Capital
    30-Day Payment Velocity
    Week 8 (current)
    Fintech Payment Infrastructure Operational
    💱
    50–150 bps
    FX Rate Efficiency Advantage
    🏦
    Sponsor Local Bank Account
    Source currency · Single instruction
    Fintech Payment Partner
    Optimised FX routing · Multi-currency disbursement
    🏥
    Investigator Sites (Global)
    Local currency · Seamless receipt
    06

    Fintech Payment Orchestration

    Verified payables are disbursed through optimized local payment rails across APAC markets, with FX transparency, multi-currency support, and same-day to next-day settlement capability for most corridors.

  • Local payment rail optimization per market
  • Real-time FX rate transparency with cost disclosure
  • Multi-currency disbursement in local denominations
  • Payment status tracking from instruction to receipt
  • Failed payment automated retry and escalation protocols
  • End-to-End Platform Architecture

    A layered infrastructure design — from data ingestion to payment disbursement — built for regulatory compliance, operational resilience, and APAC-scale performance.

    Layer 1 — Data Sources
    EDC
    Site Portal API
    Protocol Budgets
    Clinical Trial Agreements
    ⬇ Unified Data Ingestion Layer (Real-time + Batch)
    Layer 2 — Intelligence & Reconciliation
    Budget Intelligence Engine
    AI Reconciliation Engine
    Confidence Scoring
    Explainability Engine
    Audit Log Immutable Store
    ⬇ Continuous Payable Formation
    Layer 3 — Funding & Authorization
    Dynamic Funding Engine
    Sponsor Authorization Portal
    RBAC Controls
    Compliance Gateway
    ⬇ Payment Instruction Formation
    Layer 4 — Payment Rails & Disbursement
    Fintech Payment Partner
    SWIFT Corridors
    FX Engine
    Efficient FX Rates
    ⬇ Confirmed Receipt
    Layer 5 — Reporting & Compliance
    Sponsor Dashboard
    CRO Reporting Portal
    Site Payment Dashboard
    Regulatory Audit Package
    Accrual Reports
    Compliance Infrastructure: 21 CFR Part 11 ICH E6(R3) GDPR SOC 2 Type II AES-256 Encryption
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    See the Platform in Action

    Our implementation team will walk through your current payment stack and show you exactly how ClinTrust.ai integrates with your existing EDC and CTMS systems.